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胆道闭锁及相关疾病

Biliary atresia and associated disorders

ORPHA:498345疾病组中国目录 第2批 · 16

近两年的全球研究 53L2

2024/08 起在 Europe PMC 检索所得,按发表时间倒序显示最近 20 篇。本病的检索词较宽泛,命中数可能偏高,请以标题为准。标题未译成中文——自动翻译需要接入 LLM 服务,尚未引入。

  • 2026-06开放获取
    Altered Serum Concentrations of Fat-Soluble Vitamins in Dogs with Inflammatory Protein-Losing Enteropathy
    Animals : an open access journal from MDPI
  • 2026-06
    Abstract
    JPGN reports
  • 2026-05综述开放获取
    From tradition to evidence: medicinal plants used for childhood diseases in the Ehlanzeni District, Mpumalanga Province, South Africa
    Frontiers in pediatrics · DOI · Europe PMC
  • 2026-04病例报告开放获取
    Pediatric Focal Nodular Hyperplasia Mimicking Hepatic Metastasis from Wilms Tumor: A Case Report
    Surgical case reports · DOI · Europe PMC
  • 2026-04综述开放获取
    Decoding Rho GTPase signalling networks in directed cell migration
    Frontiers in cell and developmental biology · DOI · Europe PMC
  • 2026-04开放获取
    Posttraumatic growth in parents of children who underwent liver transplantation: a cross-sectional study
    BMC psychology · DOI · Europe PMC
  • 2026-04开放获取
    Targeting FGG alleviates cholestatic fibrosis by inhibiting hepatic stellate cell activation and regulating macrophage homeostasis
    Journal of nanobiotechnology · DOI · Europe PMC
  • 2026-04开放获取
    2024 National Clinical Database annual report by the Japan surgical society
    Surgery today · DOI · Europe PMC
  • 2026-02预印本
    Cystic Biliary Atresia Combined with Gallbladder Duplication: A Case Report
    · DOI
  • 2026-02开放获取
    Differences in Mortality by Donor Sex and Age in a Multinational Cohort of Liver Transplant Recipients
    Transplantation direct · 被引 1 · DOI · Europe PMC
  • 2026-02开放获取
    Transplacental Transfer of Telbivudine in Hepatitis B Virus-Infected Pregnant Women Treated with Telbivudine during the Third Trimester
    ACS omega · DOI · Europe PMC
  • 2026-01
    Balloon-Assisted <i>n</i>-Butyl Cyanoacrylate Filling of Saccular Portal and Splenic Vein Pseudoaneurysms
    Journal of endovascular therapy : an official journal of the Internati · DOI · Europe PMC
  • 2025-12开放获取
    A comparative study of portoenterostomy and choledochojejunostomy in New Zealand rabbits under immunosuppression
    Frontiers in surgery · DOI · Europe PMC
  • 2025-12开放获取
    Serum Liposoluble Vitamins (A, D, E) in Dogs with Chronic Biliary Tract Diseases Versus Healthy Dogs
    Veterinary sciences · DOI · Europe PMC
  • 2025-11开放获取
    Efficacy of primary endoscopic ultrasound-guided biliary drainage with the placement of multiple plastic stents in the management of hepaticojejunostomy stricture: a retrospective, single-center study in Japan
    Clinical endoscopy · DOI · Europe PMC
  • 2025-11开放获取
    Intraoperative transesophageal echocardiography under aortic arch branch blood flow monitoring in a patient with an aberrant left subclavian artery: a case report
    JA clinical reports · DOI · Europe PMC
  • 2025-11综述
    Successful Obstetric Outcome in a Woman with Prior Kasai Procedure for Biliary Atresia and Concurrent Alpha-1 Antitrypsin Deficiency: A Case Report
    Nigerian medical journal : journal of the Nigeria Medical Association · Europe PMC
  • 2025-10开放获取
    Association of maternal biliary disease with hepatopancreatobiliary morbidity in offspring
    Journal of pediatric gastroenterology and nutrition · 被引 1 · DOI · Europe PMC
  • 2025-10病例报告开放获取
    Gallstone Obstruction in Roux-en-Y Hepaticojejunostomy: An Unusual Challenge After Liver Transplant for Biliary Atresia
    ACG case reports journal · DOI · Europe PMC
  • 2025-09开放获取
    Clinical application of single nucleotide polymorphism array in prenatal diagnosis: Experience with 8753 samples
    PloS one · DOI · Europe PMC

在中国开展的临床试验 20L2

按病名在 ClinicalTrials.gov 检索、并校验研究中心含中国大陆而来。登记状态不等于现在真的能入组——务必按 NCT 号到原站核实,并与主治医生商量。

登记为可入组 5

  • 招募中NCT05072626
    High Medium-chain Triglyceride Nutritional Support in Infants With Biliary Atresia
    观察性 · 2021/10/11Children's Hospital of Fudan University
    中国研究中心 1 个:Shanghai
  • 仅邀请入组NCT05426733
    An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia
    III 期 · 干预性 · 2022/07/05Albireo, an Ipsen Company
    中国研究中心 2 个:Guangdong、Shanghai
  • 招募中NCT05925309
    Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai Portoenterostomy
    不适用 · 干预性 · 2023/07/01Children's Hospital of Fudan University
    中国研究中心 1 个:Shanghai
  • 招募中NCT05848310
    Preoperative Serum FGF19 in the Prognosis of Biliary Atresia
    观察性 · 2023/10/15Children's Hospital of Fudan University
    中国研究中心 1 个:Shanghai
  • 招募中NCT06764082
    Nutritional Intervention for Biliary Atresia
    不适用 · 干预性 · 2025/02/01Tongji Hospital
    中国研究中心 1 个:Wuhan
其他状态的试验(15 项)
  • 状态未知NCT03842150
    Development and Validation of a Screening Score for the Biliary Atresia in Infantile Cholestasis: A Prospective Study
    观察性 · 2014/06/01Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
    中国研究中心 1 个:Shanghai
  • 状态未知NCT02503384
    Clinical and Basic Study for Pediatric Liver Transplantation
    观察性 · 2015/07RenJi Hospital
    中国研究中心 1 个:Shanghai
  • 状态未知NCT05909033
    Early Predictors for the Short Term Native Liver Survival in Patients With Biliary Atresia After Kasai Procedure
    观察性 · 2017/05/20Weibing Tang
    中国研究中心 1 个:Nanjing
  • 状态未知NCT03563378
    Effects of Intraoperative Normal Saline vs Lactated Ringer on Outcomes in Pediatric Liver Transplantation
    不适用 · 干预性 · 2018/07/28RenJi Hospital
    中国研究中心 1 个:Shanghai
  • 已撤回NCT03898765
    Dry Blood Spot Screening Test for Biliary Atresia(DBS-SCReBA)
    不适用 · 干预性 · 2019/04/01Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
    中国研究中心 1 个:Shanghai
  • 已完成NCT04336722
    Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD)
    III 期 · 干预性 · 2020/07/08Albireo, an Ipsen Company
    中国研究中心 2 个:Guangzhou、Shanghai
  • 状态未知NCT05181332
    Predictive Models of Hepatic Decompensation and Survival Outcomes in Pediatric Patients With Cirrhosis
    观察性 · 2021/01/01West China Hospital
    中国研究中心 1 个:Chengdu
  • 已完成NCT04370145
    Antibiotics Treatment of Cholangitis Post-Kasai Portoenterostomy
    IV 期 · 干预性 · 2021/05/01Tongji Hospital
    中国研究中心 2 个:Wuhan
  • 已完成NCT04524390
    Evaluation of Maralixibat in Biliary Atresia Response Post-Kasai
    II 期 · 干预性 · 2021/07/08Mirum Pharmaceuticals, Inc.
    中国研究中心 5 个:Beijing、Guangzhou、Hanzhou、Shanghai
  • 状态未知NCT05464303
    Definition for Biliary Atresia Associated Cholangitis After Surgery
    观察性 · 2022/07/15Nanjing Children's Hospital
    中国研究中心 1 个:Nanjing
  • 已完成NCT05503394
    A Peer Support Network System Construction for the Primary Caregivers of Children With Biliary Atresia
    不适用 · 干预性 · 2022/08/31Children's Hospital of Fudan University
    中国研究中心 1 个:Shanghai
  • 状态未知NCT05783518
    Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients
    IV 期 · 干预性 · 2023/03/27Tianjin First Central Hospital
    中国研究中心 1 个:Tianjin
  • 状态未知NCT06219993
    Robot-assisted Modified Kasai Portoenterostomy Versus Open Kasai Portoenterostomy for Biliary Atresia
    观察性 · 2023/12/21Zunyi Medical College
    中国研究中心 2 个:Zunyi
  • 已终止NCT06121375
    Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy
    II 期、III 期 · 干预性 · 2024/09/02Intercept Pharmaceuticals
    中国研究中心 5 个:Guangzhou、Hangzhou、Shanghai、Taiyuan
  • 已完成NCT07328204
    Kasai Portoenterostomy Timing and Outcomes in Biliary Atresia
    观察性 · 2025/12/01The Children's Hospital of Zhejiang University School of Medicine
    中国研究中心 1 个:Hangzhou

中国境外的在招试验 22L2

这些试验在中国没有研究中心,通常无法直接报名——入组一般要求在当地居住并接受随访。列在这里是因为它另有用处:看清楚全世界正在试哪些药、做到了哪一期、由谁在做。把药名和 NCT 编号记下来去问主治医生,或据此进一步查该药是否已在境外获批、是否有拓展性用药(expanded access)通道。

美国7法国2加拿大2瑞士1印度尼西亚1英国1埃及1巴基斯坦1土耳其1丹麦1澳大利亚1

CT.gov 报告命中 22 项,此处取回并展示最近的 15 项。

  • 尚未开始招募NCT06260566
    Tolerability of Enteral NAC in Infants
    I 期 · 干预性 · 2026/10Sanjiv Harpavat
  • 招募中NCT06506734
    Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia
    观察性 · 2026/04/07University Hospital, Toulouse
    法国
  • 招募中NCT07250854
    The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis
    早期 I 期 · 干预性 · 2026/01/23University of Alabama at Birmingham
    美国
  • 尚未开始招募NCT07129655
    Cholangitis Definition and Treatment After Kasai Hepatoportoenterostomy for Biliary Atresia: TRACK-BA Study (TRacking Cholangitis Post Kasai in Biliary Atresia)
    观察性 · 2025/10/01University Hospital, Geneva
    瑞士
  • 尚未开始招募NCT07139717
    Stool Card in Biliary Atresia
    观察性 · 2025/09/01Assiut University
  • 尚未开始招募NCT07011199
    Clinical Outcomes of Early Kasai Surgery With Umbilical Cord MSCs in Biliary Atresia
    I 期 · 干预性 · 2025/06/17Universitas Diponegoro
    印度尼西亚
  • 招募中NCT07697872
    The Dirty Nappy Study
    观察性 · 2025/04/01Birmingham Women's and Children's NHS Foundation Trust
    英国
  • 招募中NCT06708572
    Evaluation of the Use of Granulocyte Colony Stimulating Factor (GCSF) in Post Kasai Type 3 Biliary Atresia
    不适用 · 干预性 · 2024/12National Liver Institute, Egypt
    埃及
  • 招募中NCT07513038
    Use of Indocyanine Green (ICG) for the Diagnosis of Biliary Atresia
    I 期、II 期 · 干预性 · 2024/08/01Boston Children's Hospital
    美国
  • 招募中NCT07709702
    ERAS in Choledochal Cyst & Biliary Atresia
    不适用 · 干预性 · 2024/07/27Muhammad Zubair Shoukat
    巴基斯坦
  • 招募中NCT06564740
    Stem Cell Applications in Biliary Atresia Patients
    不适用 · 干预性 · 2024/06/01Necmi Kadıoğlu Hospital
    土耳其
  • 招募中NCT04272515
    Molecular Characterization for Understanding Biliary Atresia
    不适用 · 干预性 · 2021/02/07Institut National de la Santé Et de la Recherche Médicale, France
    法国
  • 招募中NCT05399745
    BILACO Trial: Biliary Atresia - a Severe Complex Congenital Liver Disease
    观察性 · 2020/03/01Rigshospitalet, Denmark
    丹麦
  • 招募中NCT03273049
    Mapping Disease Pathways for Biliary Atresia
    观察性 · 2016/07/21University of Pittsburgh
    美国
  • 招募中NCT01793168
    Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
    观察性 · 2010/07Sanford Health
    澳大利亚、美国

外部标识与链接

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本页数据来源

  • 疾病定义、同义词、基因、表型、流行病学:Orphanet(CC BY 4.0)
  • 中文病名:Orphanet 中文包,冻结于 2020-06-01
  • 表型中文标签:HPO 简体中文翻译(CHPO 上游成果)